The gang visits the Brainsplosion video game company, after they offer Velma a high-paying position working on a new video game Protein Titans 2. However, she is reluctant to accept the position, because it would mean no longer traveling with the gang. Meanwhile, the ghost chef, a villain from the Protein Titans 2 comes to life and the gang tries to solve the mystery, whilst Velma is making her decision.

Protein Titans 2