After a crime prevention talk at school, Dee Dee, Lee Lee, and Mee Mee become crime fighters, but they unintentionally end up being neighborhood criminals.
Dexter travels to the moon and finds that aliens are planning an invasion on Earth, and he uses his Robo-Dexo 2000 to stop them. It turns out that they only were interested in purchasing sweaters for the winter.
After Dexter’s pencil rolls to the back of the school bus, Dexter goes to retrieve it, but legend says that no one has ever returned from the back of the bus.
Dexter is disappointed when he ends up at an Amish farm instead of a high-tech farm for summer camp. His attempts to modernize the Amish family do not go well.
When Dexter is asked to bring his mother to school, he disguises Dee Dee as her so that she can take her place, but Dee Dee does not behave like their mother.
Dee Dee’s stuffed animals come to life and roam the house when Dee Dee uses a formula that brings inanimate objects to life, which delights Dee Dee, much to his dismay.
In a parody of Tom and Jerry, Dexter accidentally switches his brain with that of a mouse’s and must avoid his mother when she decides to exterminate him.
When Dexter’s friends become tired of his complicated traps and cheating while playing a role-playing game, they put Dee Dee in his place. She changes the style of play, which annoys Dexter but impresses his friends.
When Dexter is bitten by a clown’s dentures, he begins turning into a mad clown every night, terrorizing the town with his mayhem, and only Dee Dee, who knows mime, can stop him.
Dee Dee accidentally shuts down Dexter’s lab, and he has to power it back. In the process, Dee Dee attempts to keep Dexter from finding out what she really did.
Dexter catches the chicken pox, and Dee Dee tells him a ridiculous tale that if he keeps scratching them, he will turn into an evil chicken. Dexter completely restrains himself so that he will not have to scratch it; unfortunately, he is unable to resist and his nonstop scratching eventually does just that.
On Mother’s Day, Dexter’s mother has her gloves taken by the family so that she can relax and not do housework, but she is unable to adjust to a life where she cannot keep the house clean.
Mandark disguises himself as Dexter’s mom to get into Dexter’s Lab. Unfortunately for Mandark, he now has to deal with Dexter, Dad, and Dee Dee’s requests, which are too much for him.
On his birthday, Dexter makes himself invisible so that he can find out whether his parents have bought him the Major Glory action figure he always wanted.
Created and narrated by a six-and-a-half-year-old boy named Tyler Samuel Lee, who sent a tape containing the episode’s audio to Cartoon Network,[9] the story follows Dexter and Mandark’s robot “brother” Computress teaming up to make Mandark’s head shrink.