Dee Dee’s stuffed animals come to life and roam the house when Dee Dee uses a formula that brings inanimate objects to life, which delights Dee Dee, much to his dismay.
Dexter creates a new type of ink that lets him command people to do whatever he wants. However, when Mandark gets his hands on it, Dexter is the one that becomes commanded.
Dexter’s father sleepwalks into Dexter’s lab. Dexter discovers this, and now has to escort him out of the lab without waking him up, which proves more difficult than thought.
When Dee Dee tries to cut off a piece of her hair, she accidentally cuts off one of her pigtails. Dexter gives her a potion to make her missing hair grow back. However, Dee Dee squirts too much of it in her hair, and Dexter must return Dee Dee’s hair back to normal.
Dexter, Monkey, Agent Honeydew, the Justice Friends, Dee Dee, her imaginary friend Koosalagoopagoop, Mandark, his parents, and Dexter’s parents participate in a cross-country race a la Wacky Races.
Dexter catches the chicken pox, and Dee Dee tells him a ridiculous tale that if he keeps scratching them, he will turn into an evil chicken. Dexter completely restrains himself so that he will not have to scratch it; unfortunately, he is unable to resist and his nonstop scratching eventually does just that.
Dexter is forced to take Dee Dee to the zoo. There, she ends up trying to save an ostrich with disastrous results. Dee Dee and the ostrich switches their places.
Dexter decides to work with Mandark, but finds himself doing all of the work. In the end, Mandark tries to press the button when Dexter connects the plug in the outlet to bring his show title back.