At a zoo, an artistic monkey paints Tom to look like a tiger after he accidentally wrecks his art during a chase against Jerry. As a result, Tom manages to scare Jerry as well as everyone else and every animal at the zoo with his tiger look.
Tom works at a zoo run by Spike, who orders him never to feed the zoo’s animals (only Spike can) or else he will have his badge. However, Jerry inadvertently and constantly causes trouble by framing Tom while he tries to prevent Jerry from feeding them.
Spike and his girlfriend Toodles mistake Tom and Jerry for valets, as a result of which upon leaving their car to be parked while checking themselves in a hotel, Tom and Jerry unwillingly go on a wild and elaborate joyride across town.
After accidentally trashing a fancy hotel lobby during another chase against Jerry, Tom is hired as a bellboy by the hotel’s manager in order to pay for the damages. Unfortunately, Jerry makes Tom’s assignments difficult.
While listening to his favorite hip hop music, Jerry gets disrupted by the noise of the city, so he moves out of town to a farm owned by Tom. As a result, his music causes Tom’s pet hen to lay eggs quickly.
A sequel to Pecos Pest (1955), Jerry’s uncle, Pecos Pest, returns to Tom and Jerry’s house for a visit, where he constantly sings and plays on his guitar, annoying and keeping both Tom and Jerry awake.
Formerly poor, Tom and Jerry become rich overnight shortly after their numbers come in, so they split their millions and each set out to build a mansion across from each other.